Nena joined the IFRC in October 2020, having worked on global development issues such as climate change, gender, and fragile and conflict-affected situations for over 30 years. This includes through her previous role as Vice President for Asia and Pacific for the International Finance Corporation (IFC).

At the IFC, Nena promoted development finance innovation in a variety of leadership roles, including efforts to build a new architecture for development finance with other institutions, governments and the private sector. She helped shape the World Bank Group strategy, working with the International Development Association on a pioneering private sector window to catalyse greater private investment in low-income and conflict-affected countries.